The Union Square campus is a collaborative effort between the nursing programs of UNC Greensboro, NC A&T State University and Guilford Technical Community College in addition to the regional healthcare system, Cone Health.

The campus will ultimately include multiple buildings. Phase One is an 85,000-square-foot building housing 10 state-of-the-art simulation laboratories and training spaces for students. The simulated hospital includes an OR suite, an LDRP suite, an ICU suite and MED/SURG suite. Other functional areas include faculty offices, a medical educational / nursing library, 150 seat tiered classroom, 100 classroom, and a 380 seat auditorium.